Bangladesh Army International University of Science and Technology

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Czech Republic, Brno

Department:Marek Mráz Research Group?–?Central European Institute of Technology
Deadline:?15 Jan 2025
Start date:?early 2025 (to be negotiated)
Job type:?full-time
Job field:?Science and research

Come to CEITEC MU in Brno and join us!

We are passionate molecular biologists at CEITEC looking for

Postdoctoral Researcher

in?Lymphoid Microenvironment Models And Their Use To Study Targeted Therapy And Resistance In B Cell Malignancies

About this position:

You will work in a?team of young investigators that challenge major problems in the field of hematology. We do basic and translational science, but with the objective to help patients in the future (we have access to primary samples with hem. malignancies, and mouse models).

Chronic lymphocytic leukemia (CLL) cells and indolent lymphomas rely on microenvironmental signals for survival, proliferation, and therapy resistance. CLL cells undergo apoptosis in vitro, necessitating microenvironment models for long-term culture and proliferation studies. Existing in vitro and in vivo models, based on coculture with T-lymphocytes or stromal cells, mimic some aspects of the natural microenvironment but have limitations.

This?research aims to develop and optimize models replicating the lymphoid microenvironment to study new therapeutic strategies, including drugs targeting CLL proliferation, resistance mechanisms, and combinatory approaches not feasible in conventional cultures. A?recently developed co-culture model enables robust CLL cell proliferation. Using primary patient samples and cell lines, the project will employ functional assays, RNA sequencing, genome editing, and drug screening to explore microenvironmental dependencies and resistance to targeted therapies.

The candidate profile:


	Motivated smart person with "drive" to work independently, but also willing to learn from other people in the lab and collaborate
	Having degree in Molecular biology, Biochemistry, or similar field and have deep interest in molecular biology and cancer cell biology


What you will learn and do:


	Think and work independently as a?scientist, design experiments and formulate hypothesis
	Write of abstracts and papers (and course in grant writing and presentation of data)
	Attend conferences to present your research
	Spend 1-2 months visit(s) in collaborating labs in Europe or US
	Collaborate with experts in wet lab research and bioinformatics
	Critically analyze scientific data (regular journal clubs)
	Classical and novel methods of molecular biology (e.g. RNAseq, Crispr, Cut&Tag, mouse mdoels, immunoblotting, flow cytometry, qRT-PCR, cell cultures, cloning), and you will use our in vitro models for microenvironmental interactions, and artificial activation/inhibition signalling pathways to decipher the gene regulatory loops
	Supervise students, if interested


?What we provide to you:


	Open access to CEITEC MU core facilities with state-of-the-art equipment and experienced staff
	Full contract for Post-Docs with competitive salary (funded by ERC grant)
	Flexible working hours
	Support for further education and professional development
	Benefits package: 6 weeks of paid holiday, medical insurance, financial contribution to meal and kindergarten/pension scheme, Multisport card, mental health care, sports at the campus
	Kindergarten Elánek in Campus
	Support in these areas:
	
		Welcome Office service?before and after arrival
		Grant Office?support
		Postdoc Peer Committee
		CEITEC events?–?workshops, conferences, lectures, training, family gathering?etc.
		More at?Why work at CEITEC MU?
	
	


How to apply?

Application deadline:?15.1.2025

Start date: early 2025?(to be negotiated)

Contact the PI and submit a?CV by email to:?marek.mraz2@email.cz


Masaryk University

Morocco

CRSA – Postdoc in Enhanced water balance modeling scheme over Morocco

About UM6P:
Located at the heart of the future Green City of Benguerir, Mohammed VI Polytechnic University (UM6P), a higher education institution with international standards, is established to contribute to the development of Morocco and the African continent. Its vision is honed around research and innovation at the service of education and development. This unique nascent university, with its state-of-the-art campus and infrastructure, has woven a sound academic and research network, and its recruitment process is seeking high-quality academics and professionals in order to boost its quality-oriented research environment in the metropolitan area of Marrakech.

About CRSA:
CRSA is a transversal structure across several UM6P Programs. Research within the center is organized around several major areas that aim to ensure the challenging Food and Water security goal in Africa, with a special focus on developing methods/tools that use multi-source remotely sensed data. The research aims to improve our understanding of the integrated functioning of continental surfaces and their interaction with climate and humans, with emphasis on sustainable management of natural resources (soil, land, water, agriculture) in the context of Climate Change. One of the center’s goals is to provide a set of services and operational products to users (local, national, and international) that aid in the decision support of water and food systems.

Job Description:
For sustainable management of water resources, it is crucial to be able to accurately quantify the evolution of surface and groundwater storage. For a long time, the main tools for providing such information for planning purposes have been hydrological models. They come in various configurations, from simple, conceptual lumped models to more complex, distributed ones. Their low input data requirements and flexible application make them widely used by water managers. While very attractive, these models can be pretty challenging when attempting to compute the water budget over broader regions, mainly in ungauged catchments. Being developed for specific contexts, the structure of these models, depending on the dominant regime and its dynamics, put more focus on a specific water balance component than others. This can make the structure inadequate to be directly transferred to other regions with different physiographic contexts and hydroclimatic regimes. The most recent advances in large-scale gridded hydrometeorological data with relatively high spatio-temporal resolution offer an unprecedented opportunity to address some of these issues, particularly with the extensive emergence of data-driven modeling approaches.

In this perspective, we are looking for a highly motivated postdoctoral researcher to join our Center for Remote Sensing Applications team. The successful candidate will work on implementing a hybrid modeling scheme driven by remote sensing data to enhance the estimation of some of the significant water balance components. The candidate is expected to seek an optimal integration between the physical representations of the various processes and the computing power of the AI algorithms.

Key duties
1.?? ?Develop a robust framework to simulate streamflow decomposed into fast-flow and baseflow at multiple Moroccan watersheds. The candidate would have to test various fast-flow and, more importantly, baseflow simulation methods and outline their adequacy depending on physiography and climate conditions.
2.?? ?Implement an enhanced snow balance modeling scheme employing multisource remote sensing data. The candidate will consider and investigate the existing tools and then suggest an enhanced prediction scheme of the snow dynamics (snow accumulation and snowmelt) over the Atlas Mountain range.
3.?? ?Make use of the developed modeling scheme to outline the drainage area's contribution to the storage changes of surface and underground reservoirs.
4.?? ?Better identify the contribution of rainfall and snowmelt.
5.?? ?Design and conduct fieldwork for in-situ measurements and samplings.
6.?? ?Closely work with researchers and students involved in spatial hydrology.
7.?? ?Publish scientific papers in peer-reviewed journals and deliver presentations and progress reports.
8.?? ?Contribute to the supervision of Masters and Ph.D. students.
Qualifications:
??? ?Ph.D. in Spatial Hydrology, Environmental sciences, Earth sciences, or related fields
??? ?Strong background in hydrology and remote sensing techniques.
??? ?Proficiency in computer programming tools such as Matlab and/or Python.
??? ?Knowledge of statistics and mathematical modeling.
??? ?Experience in large spatial data processing, analysis, and interpretation.
??? ?Experience in running and evaluating environmental models.
??? ?Good publication record.
??? ?Good speaking and writing communication skills.
??? ?Ability to collaborate with other team members and UM6P departments.


Mohammed VI Polytechnic University

United Kingdom, Southampton

Programmer (python/C) in the Collaborative Computing Project 4 Macromolecular Crystallography.

We look for a programmer in the field of macromolecular crystallographic computing. We seek to develop, implement, and apply methodology for identification and examination of multiple structural states and conformations for this, and will employ the Bayesian decomposition we have developed. Any development is to be implemented within the programs servalcat/refmac for the CCP4 computing programming suite and released publicly.

The successful candidate will be knowledgeable in crystallographic theory and able to code. The post will be based at Southampton with regular research visits to the LMB Cambridge and to the Research Complex at Harwell for interaction with the CCP4 core team. The project has a focus on time resolved work and cooperates with the UK XFEL hub at the Diamond Light Source. This contract is initially 15 month, but may be extended.

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of?Senior Research Assistant?will be given.


University of Southampton

India, Delhi

Overview

The University of Southampton, in partnership with Oxford International Education Group (OIEG), is launching its first international campus in India, located in Gurgaon, Delhi. This initiative is a response to India's New Education Policy and represents a significant investment in transnational education. The new campus aims to provide Indian students with the opportunity to earn a globally recognised degree without leaving the country.

Job purpose

The role holder’s contribution will be central to delivery and support of teaching, learning and assessment, across Finance and Accounting for the University of Southampton Delhi.

The role holder will teach at undergraduate and postgraduate level and engage in other necessary educational activities to ensure successful delivery of degree programmes. Once teaching activities are embedded and successful the role holder will undertake research and knowledge exchange in line with the campus’s research strategy.

The role holder will undertake leadership, management and engagement activities and will demonstrate collegiality by ensuring ‘Southampton Behaviours’ are embedded within their ways or working.

They will be committed to high-quality education and support of learning and to building a vibrant student experience and community. Visible and collegiate, the role holder will be expected to contribute to all aspects of the campus’s activities including student recruitment and outreach.

For further details and how to apply click?here.


Finland, Helsingfors (Helsinki)

The HiLIFE - Institute of Biotechnology (BI) is a research institute that operates at the highest international level. It includes 40 research groups and 250 researchers. The Institute is situated in the Viikki science park. For more information on the Institute, please visit https://www.helsinki.fi/en/hilife-institute-of-biotechnology.

The HiLIFE - Institute of Biotechnology, Johanna Syrj?nen laboratory group invites applications for a?

POSTDOCTORAL RESEARCHER

Our lab works on understanding the molecular basis for cellular communication and signaling. We use a multidisciplinary approach by combining structural biology, biochemistry, and biophysics techniques to address fundamental questions in this field.

The successful applicant will join a project funded by the Research Council of Finland to investigate the micronutrient scavenging mechanisms of pathogenic fungi. They will focus on the structural and functional characterization of membrane protein complexes involved in zinc scavenging.

About the position

We are seeking a highly motivated postdoctoral researcher with a background in molecular biology, protein expression and protein purification, as well as experience in structural biology. Experience of single particle cryo-EM or working with membrane proteins is highly desirable but not required. The ideal candidate should have strong interpersonal skills, be able to work collaboratively in a team and be adaptable to the different types of tasks and techniques throughout the project. They should also have excellent communication skills in English.

Further degree requirement for postdoctoral position: The degree requirement must be met by the beginning of the employment.

The position is for 3 years starting in early 2025 or as agreed. A trial period of 6 months will be applied, and the salary will be based on the Universities salary scheme for teaching and research personnel composed of both task specific and personal performance components. The starting salary is ca. 3700 – 4300 euros, depending on the qualifications and experience of the applicant.

What we offer

We offer an opportunity to work in an exciting, ground-breaking project funded by the Research Council of Finland. We have an enthusiastic, collaborative, and inclusive work environment. Our lab is part of the Biomolecular Structure and Function Research Program at the Institute of Biotechnology.

We value mentorship and training. The applicant will be supported in postdoctoral fellowship applications (such as EMBO, Marie Sk?odowska-Curie, etc.) and will have the opportunity to present their research at national and international conferences.

As well as infrastructure for biochemical and biophysical characterization of proteins, we benefit from an in-house 200 kV Talos Arctica microscope fitted with a Falcon 4i camera for screening and data collection. We also have access to data collection on Titan Krios 300 kV cryo-electron microscopes at international facilities.

Finland is a member of the EU, has high quality free schooling (also in English), generous family benefits and healthcare, and was recently ranked as the best country in the world for expat families and in the world’s top ten most livable cities. Finland and the Helsinki region possess top expertise in sciences in terms of a vibrant talent pool, leading research, strong support services and functioning collaboration networks. For more information about working at the University of Helsinki and living in Finland, please see helsinki.fi/en/university/working-at-the-university.

How to apply

The deadline for the applications is 31.12.?but the position will be filled immediately once a suitable candidate has been identified.

Application should include the following documents as a single pdf file: CV (with the names and contact details of 2-3 referees), list of publications, and a motivation letter describing your current/past projects, career goals, what you would like to learn from the Syrj?nen lab and what you might bring to the Syrj?nen lab.

Please submit your application, together with the required attachments, through the University of Helsinki electronic recruitment system by clicking on the ‘Apply for job’ button. Applicants who are employees of the University of Helsinki are requested to leave their application via SAP Fiori.

For further information and inquiries please contact Group Leader Johanna Syrj?nen (email: johanna.syrjanen@helsinki.fi). For further information on the recruitment system or process, you may contact HR Partner Anu Roine (anu.roine@Helsinki.fi).?

Helsinki Institute of Life Science

Helsinki Institute of Life Science (HiLIFE) is a research institute established in 2017 that supports high quality life science research across the University campuses and faculties. HiLIFE builds on existing strengths and new recruits and partnerships to create an attractive international environment for researchers to solve grand challenges in health, food, and environment. HiLIFE coordinates research infrastructures in life sciences and provides research-based interdisciplinary training.

University of Helsinki

The University of Helsinki, founded in 1640, is one of the world’s leading universities for multidisciplinary research. The university has an international academic community of 40,000 students and staff members. The University of Helsinki offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and professional development opportunities. The International Staff Services office assists employees from abroad with their transition to work and life in Finland.

Do you have a helsinki.fi username and a valid employment contract, a grant researcher's contract, a visiting researcher's or visiting professor's contract at the University of Helsinki? Log in here to apply to our open positions.


University of Helsinki

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Bangladesh Army International University of Science and Technology